Modelling impact of TB vaccination vs other interventions/policies
Creating evidence to support tuberculosis decision-makers in reducing the global burden of Tuberculosis
Modelling
Impact of targeted tuberculosis vaccination among a mining population in South Africa: A model based study
We developed an individual-based TB transmission model representing a hypothetical population consisting of people who worked in South African gold mines or lived in associated labor-sending communities. We simulated the implementation of a postinfection adult vaccine with 60% efficacy and a mean effect duration of 10 years.
Potential impact of spatially targeted adult tuberculosis vaccine in Gujarat, India
we aimed to estimate the impact of vaccine delivery strategies that were targeted to high-incidence geographical 'hotspots' compared with randomly allocated vaccination. We developed a spatially explicit mathematical model of TB transmission that distinguished these hotspots from the general population.
The health and economic benefits possible with novel tuberculosis vaccines – A modeling study in India and Indonesia
We estimated gains possible with novel post-exposure vaccines, in India and Indonesia. We modeled vaccine impact on TB incidence, TB mortality, and on national income growth and the intrinsic value of living longer, known as Full-income.
The epidemiologic impact and cost-effectiveness of new tuberculosis vaccines on multidrug resistant tuberculosis in India and China
We investigated the epidemiologic impact, cost-effectiveness, and budget impact of hypothetical novel prophylactic prevention of disease TB vaccines on RR/MDR-TB in China and India.
Making wider use of the world’s most widely used vaccine: Bacille Calmette-Guerin revaccination reconsidered
This paper assesses the effectiveness and cost-effectiveness of revaccinating adolescents in a setting with intense transmission—Cape Town, South Africa.
New tuberculosis vaccines in India: Modelling the potential health and economic impacts of adolescent/adult vaccination with M72/AS01E and BCG-revaccination
We estimated the potential health and economic impact of M72/AS01E and BCG-revaccination in India and investigated the impact of variation in vaccine characteristics and delivery strategies.
Mixed vaccination strategy for the control of tuberculosis: A case study in China
This study first presents a mathematical model of TB transmission considering BCG vaccination compartment to investigate the transmission dynamics nowadays
Epidemiological impact of targeted interventions for people with diabetes mellitus on tuberculosis transmission in India: Modelling based predictions
We aimed to assess the impact on TB disease of several intervention strategies targeting people with DM in India.
Impact and cost-effectiveness of new tuberculosis vaccines in low- and middle-income countries.
To aid in prioritizing the development of tuberculosis (TB) vaccines most likely to reach the 2050 TB elimination goal, we estimated the impact and cost-effectiveness of a range of vaccine profiles in low- and middle-income countries.