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Preparing the landscape for TB vaccines: South Africa’s strategic planning

The South African TB Think Tank is a national collaboration of TB stakeholders, including researchers, policymakers, clinicians, and civil society. Chaired by the Chief Director of the National TB Programme (NTP), members consolidate TB research through several technical task teams, providing evidenced-based policy recommendations to the Department of Health. To support the national TB vaccine initiative, the TB Think Tank provided recommendations for the recently released NTP Strategic Plan, 2023-28

Forecasting TB vaccine demand to support supply and procurement planning

Ongoing

We present insights from two workshops with global health funders, academics, and in country TB and vaccine decision-makers and estimates of potential global demand for TB vaccines using a bottom-up, constrained demand forecasting model. The model was informed by the workshops, publicly available target product profile, landscape assessment of vaccines in development, information from proxy vaccines sourced from the WHO databases and peer reviewed literature, and interviews with TB and vaccine experts

Demand insights for uptake of TB vaccine

2022

Hypothetical vaccines

Completed

Summarize the major swing factors that would determine countries’ preference and effectively drive the uptake of a TB vaccine in terms of the date of introduction and the scale of catch-up campaign to reach the steady state

TB case-finding in the context of future vaccines

2024-2027

Hypothetical vaccines

Planned

Scenarios for future TB vaccines’ characteristics within which the value and cost-effectiveness of present-day interventions can be explored