Preparing for Tuberculosis Vaccine M72/AS01E Implementation
This correction relates to the global demand forecast for the potential implementation of the M72/AS01E TB vaccine
Adults
Insights on the implementation strategies for a potential new tuberculosis vaccine in South Africa
Examines how a potential new TB vaccine could be introduced in South Africa. Interviews with 26 stakeholders explored implementation priorities, target populations, vaccine price, cost-effectiveness, regulatory approval, financing, procurement, delivery logistics, vaccine acceptability and lessons from existing vaccination programmes.
Estimating the population impact of new tuberculosis vaccines depending on efficacy against infectious asymptomatic tuberculosis:
Uses a dynamic TB transmission model to estimate how the population impact of future TB vaccines changes depending on whether vaccines prevent progression to infectious symptomatic TB only, all infectious TB, or all TB disease.
Tuberculosis policy should shift focus to population-level interventions for greatest impact
Uses mathematical modelling to compare the population-level health and economic impacts of TB interventions in Brazil, India and South Africa. It highlights mass vaccination and community-wide screening as interventions with the potential for substantial epidemiological impact.
Knowledge of tuberculosis and vaccine trial preparedness in Lima, Peru
Study asseses knowledge and perception of TB among people in Lima, Peru with particular attention to their willingness and preparedness to participate in a future TB vaccine trial. It examined factors that could influence participation, including knowledge of TB, attitudes towards vaccination, and willingness to participate in research.
Research overview-2025: integrating scientific progress to accelerate global tuberculosis elimination
Reviews scientific progress in tuberculosis research during 2025 and discusses how advances across different areas can contribute to accelerating global TB eliminated including progress in tuberculosis vaccine development
How to introduce new TB vaccine in adolescents and adults: Insights from Key Stakeholders in Mozambique, Southern Africa
Assesses stakeholder perspectives on introducing a new TB vaccine in Mozambique, including with high-risk groups should be prioritised, challenges in reaching different populations, expected vaccine uptake and coverage, and appropriate delivery stategies.
Attitudes towards new tuberculosis vaccines among adults, adolescents and their caregivers in southern Mozambique
We investigated willingness to be vaccinated with a new TB vaccine in a high HIV and TB burden setting in southern Mozambique in 2024 using a mixed methods approach involving a cross-sectional survey and concurrent in-depth interviews.
Advancing national preparedness for the introduction of novel tuberculosis vaccines in South Africa
The workshop aimed to align stakeholders on priority populations and delivery strategies for future TB vaccines, identify evidence needs to inform national policy decision-making, and outline actions required to ensure timely and equitable introduction.
Anticipating tuberculosis vaccine acceptability in Kenya and South Africa
Assesses willingness to receive a new TB vaccine and explores attitudes, vaccine confidence, hesitancy, information needs and factors influencing potential uptake among adults, adolescents and caregivers in southern Mozambique. The study used surveys and in-depth interviews and found 77% willingness to receive a new TB vaccine among adults and adolescents.