Epidemiological impact Archives - Page 2 of 4

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The health and economic benefits possible with novel tuberculosis vaccines – A modeling study in India and Indonesia

2021

We estimated gains possible with novel post-exposure vaccines, in India and Indonesia. We modeled vaccine impact on TB incidence, TB mortality, and on national income growth and the intrinsic value of living longer, known as Full-income.

The epidemiologic impact and cost-effectiveness of new tuberculosis vaccines on multidrug resistant tuberculosis in India and China

2021

Hypothetical vaccines

Completed

We investigated the epidemiologic impact, cost-effectiveness, and budget impact of hypothetical novel prophylactic prevention of disease TB vaccines on RR/MDR-TB in China and India.

New tuberculosis vaccines in India: Modelling the potential health and economic impacts of adolescent/adult vaccination with M72/AS01E and BCG-revaccination

2023

BCG revaccination, M72/AS01e

Completed

We estimated the potential health and economic impact of M72/AS01E and BCG-revaccination in India and investigated the impact of variation in vaccine characteristics and delivery strategies.

Making wider use of the world’s most widely used vaccine: Bacille Calmette-Guerin revaccination reconsidered

2013

BCG revaccination

Completed

This paper assesses the effectiveness and cost-effectiveness of revaccinating adolescents in a setting with intense transmission—Cape Town, South Africa.

Mixed vaccination strategy for the control of tuberculosis: A case study in China

2017

Hypothetical vaccines

Completed

This study first presents a mathematical model of TB transmission considering BCG vaccination compartment to investigate the transmission dynamics nowadays

Epidemiological impact of targeted interventions for people with diabetes mellitus on tuberculosis transmission in India: Modelling based predictions

2020

Hypothetical vaccines

Completed

We aimed to assess the impact on TB disease of several intervention strategies targeting people with DM in India.

Estimating the epidemiologic impact of new TB vaccines in high-burden settings

2022-2027

Hypothetical vaccines, M72/AS01e

Ongoing

This is an NIH-funded study which will estimate the health impact of introducing a prevention of disease vaccine for adult and adolescents in moderate to high TB burden countries. We are developing model scenarios based on input from country stakeholders, including national TB program and immunization program officials.

Estimating the epidemiologic impact of new TB vaccines in the U.S.

2022-2024

Hypothetical vaccines

Ongoing

This is a study funded by the American Lung Association which will explore the potential impact of targeted implementation of a prevention of disease vaccine in a low TB burden country, the U.S.A.

Impact TB vaccination for PLHIV

2023

Hypothetical vaccines

Ongoing

Modelling to inform PPCs for TB VX for PLHIV

Population-level health and economic impacts of introducing Vaccae vaccination in China: a modelling study

2023

Vaccae

Completed

modelling the population-level health and economic impacts of introducing Vaccae vaccination to inform policy-makers in China