Impact TB vaccination for PLHIV
Modelling to inform PPCs for TB VX for PLHIV
LSHTM
Bridging the gap: evaluating high TB burden country data needs to support the potential introduction of TB vaccines for adolescents and adults: a workshop report
A workshop to asked high TB burden country experts about what epidemiological, impact, feasibility and acceptability data they anticipated they would need to guide TB vaccine introduction.
Estimating the potential public health value of BCG revaccination
Using previously calibrated models for India and South Africa, we simulated BCG revaccination assuming 45% prevention-of-infection efficacy, and we evaluated scenarios varying additional prevention-of-disease efficacy between +50% (reducing risk) and −50% (increasing risk).
The impact of alternative delivery strategies for novel tuberculosis vaccines in low-income and middle-income countries: a modelling study
We estimated the impact of novel tuberculosis vaccines in low-income and middle-income countries (LMICs) in several delivery scenarios.
The cost and cost-effectiveness of novel tuberculosis vaccines in low- and middle-income countries: A modeling study
We assessed future costs, cost-savings, and cost-effectiveness of introducing novel TB vaccines in low- and middle-income countries (LMICs) for a range of product characteristics and delivery strategies.
The potential impact of novel tuberculosis vaccines on health equity and financial protection in low-income and middle-income countries
We assessed the potential financial risk protection from introducing novel TB vaccines, and how health and economic benefits would be distributed across income quintiles.
Systematic review of mathematical models exploring the epidemiological impact of future TB vaccines
The aim was to provide a summary of the modeling methodology used, the characteristics of future TB vaccines explored using modeling, and the comparative epidemiological impact of such novel vaccine profiles.
New tuberculosis vaccines: advances in clinical development and modelling
We summarize the mathematical modelling literature used to inform vaccine development, focusing on models that address the epidemiologic impact of new TB vaccines. Finally,we describe the future for TB vaccines in the effort towards TB elimination
Potential implementation strategies, acceptability, and feasibility of new and repurposed TB vaccines
Our study provides crucial information for implementing novel TB vaccines in specific target groups and on country specific acceptability and feasibility. Key groups for vaccine implementation in these settings were identified, and should be included in clinical trials and implementation planning.
Acceptability and effect on public and cost-effectiveness impact
Understanding the acceptability of new TB vaccines, and their impact on health, cost-effectiveness, and budget, by socio-economic and risk group, in likely early adopter and other archetype countries.