National Institutes of Health (NIH) | Turning Discovery Into Health
Modelling impact of TB vaccination vs other interventions/policies
Creating evidence to support tuberculosis decision-makers in reducing the global burden of Tuberculosis
NIH
Feasibility of novel adult tuberculosis vaccination in South Africa: a cost-effectiveness and budget impact analysis
We conducted expert interviews to identify plausible vaccination implementation strategies for the novel M72/AS01E vaccine candidate. The strategies were defined in terms of target population, coverage, vaccination schedule and delivery mode. We modelled these strategies to estimate long-term resource requirements and health benefits arising from vaccination over 2025–2050.
Affordability of adult tuberculosis vaccination in India and China: A dynamic transmission model-based analysis
To estimate the total disability adjusted life years (DALYs) averted by the vaccination programme, we simulated a 50% efficacy vaccine providing 10-years of protection in post-infection populations between 2027 and 2050 in India and China using a dynamic transmission model of M. tuberculosis.
Impact TB vaccination for PLHIV
Modelling to inform PPCs for TB VX for PLHIV
Is neglect of self-clearance biasing TB vaccine impact estimates?
exploring the inclusion of self-clearance in models of tuberculosis affects the estimates of vaccine impact in China and India
The full value of vaccine assessments concept—current opportunities and recommendations
Building on the success of the recent applications of the FVVA framework, we see important new opportunities to maximize the future utility of FVVAs to country and global stakeholders and provide a proof-of-concept for analyses in other areas of disease control and prevention.