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Supporting countries with prioritization of new vaccine introductions (NVI) and portfolio optimization
Support countries with using multi-criteria decision analysis (MCDA) for prioritization of new vaccine introductions (NVI) (including new TB vaccines) and portfolio optimization, embedded in the NIS development process. The project's key questions are: 1. How can we best support countries with NVI including new TB vaccine prioritization regarding access to evidence, tools, technical support? 2. What criteria do countries use when prioritizing NVIs? 3. How to best align NVI prioritization with the NIS development process.
Part of Change 2.0
Actionable market intelligence, including vaccine demand forecast/scenarios, generated to strategically guide manufacturers and partners in their planning for introduction in high burden countries. The objectives include: 1. Strategic assessment of appropriate market-shaping interventions, 2.Stakeholder and decision process mapping , 3.Demand dynamics understanding and realistic market forecast development, 4. Commercialization strategy support for lead candidate(s).
Forecasting TB vaccine demand to support supply and procurement planning
We present insights from two workshops with global health funders, academics, and in country TB and vaccine decision-makers and estimates of potential global demand for TB vaccines
using a bottom-up, constrained demand forecasting model. The model was informed by the
workshops, publicly available target product profile, landscape assessment of vaccines in
development, information from proxy vaccines sourced from the WHO databases and peer reviewed literature, and interviews with TB and vaccine experts
Demand insights for uptake of TB vaccine
Summarize the major swing factors that would determine countries’ preference and effectively drive the uptake of a TB vaccine in terms of the date of introduction and the scale of catch-up campaign to reach the steady state
TB case-finding in the context of future vaccines
Scenarios for future TB vaccines’ characteristics within which the value and cost-effectiveness of present-day interventions can be explored
Conducting market analyses for new tuberculosis vaccines for adolescents and adults: A summary of one approach applied to M72/AS01E
A summary report of the methodology used in the MM Global Health Consulting (MMGH) market anlysis and the high-level findings and recommendations.