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BCG vaccine

BCG arthirtis in a patient with SCID

Highlights the risk of serious BCG complications in infants eith undiagnosed SCID. It emphasizes the need for immunodeficiency screening before BCG vacciantion to ensure safe vaccine delivery. The study is relevant to accessible TB vaccination through appropriate implementation and screeening strategies

Disseminated BCGosis in immunocompromised infants

Case series that describes disseminated BCG disease in five immunocompromised infants following BCG vaccination. It highlights the safety risks of BCG vaccination in infants with undiagnosed immunodeficiency and the importance of identifying the high-risk infants before vaccination. The findings are particularly relevant to national BCG vaccination policy and the safe implementation of TB vaccination programmes

Non-Specific Effects of Bacillus Calmette-Guérin

Systamtic review and meta-alysis evaluates whether BCG vaccination has non-specific effects beyond protection against tuebrculosis. It analyses 16 randomized controlled trials involving 34,197 participants and examines outcomes including mortality, infections and hospitalisation.

Progress and challenges in TB vaccine development

This review examines the development pipeline for new TB vaccines and the challenges involved in moving vaccine candidates from preclinical research through clinical trials and eventual introduction. It discusses different vaccine platforms and candidates, clinical trial design, immune correlates of protection, regulatory requirements, funding, and the need for coordinated development programmes. It also highlights key barriers that could delay the availability of an effective TB vaccine and discusses the priorities for accelerating vaccine development

Vaccination policies for healthcare personnel in Europe, 2026

Comparative study of vaccination policies for healthcare personnel acorss 32 European countries, examining which vaccines are recommended or mandatory, which healhtcare personnel are targeted and how policies have changed since 2018. It includes policies for BCG/TB vaccination, as well as influenza, Covid-19, hepatitis B, MMR, varicella, pertusis, and other vaccines
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