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Global Experts Urge Whole-of-Society Strategy to End Tuberculosis Ahead of World TB Day 2026

2026

A global World TB Day 2026 perspective bringing together TB experts from multiple countries to discuss strengthening TB prevention and control through health-system capacity, political commitment, financing, community engagement, research and innovation

Insights on the implementation strategies for a potential new tuberculosis vaccine in South Africa

2026

Novel TB vaccines

Examines how a potential new TB vaccine could be introduced in South Africa. Interviews with 26 stakeholders explored implementation priorities, target populations, vaccine price, cost-effectiveness, regulatory approval, financing, procurement, delivery logistics, vaccine acceptability and lessons from existing vaccination programmes.

Imprecision in tuberculosis infection outcomes

2025-2026

Novel TB vaccines

Assesses how imperfect sensitivity and specificity of TB infection tests can affect the results of non-inferiority TB vaccine trials. It uses statistical simulations to show that inaccurate infection markers can lead to a high risk of incorrectly declaring a new TB vaccine non-inferior

Tuberculosis funding cuts

2025-2050

Novel TB vaccines

Examines the potential economic consequences of reductions in international TB funding. Linked epidemiological and economic models for 79 low- and middle-income countries estimated how funding cuts could increase household costs and catastrophic TB-related expenditures.

Estimating the population impact of new tuberculosis vaccines depending on efficacy against infectious asymptomatic tuberculosis:

2026

M72/AS01e, Novel TB vaccines

Uses a dynamic TB transmission model to estimate how the population impact of future TB vaccines changes depending on whether vaccines prevent progression to infectious symptomatic TB only, all infectious TB, or all TB disease.

A Vax-Zine on New Tuberculosis Vaccines

2026

Novel TB vaccines

An educational and advocacy “vax-zine” explaining the development of new TB vaccines, the current TB vaccine landscape, and issues surrounding equitable access and future introduction. It is designed to help communities and advocates understand progress toward new TB vaccines and engage in discussions around their development and access

African Leaders Call for Greater Investment and TB Vaccine Readiness as Late-Stage Trials Advance

2026

M72/AS01e, Novel TB vaccines

Reports on an African Health and Finance Chairs meeting convened by the Global TB Caucus to strengthen political and financial preparedness for future TB vaccine introduction. Participants discussed sustainable financing, regulatory systems, manufacturing capacity, community engagement, equitable access, integrated health services and health-system resilience. The meeting also included updates on the M72/AS01E Phase III trial and highlighted the need for African countries to prepare for vaccine introduction before regulatory approval.

Attitudes towards new tuberculosis vaccines among adults, adolescents and their caregivers in southern Mozambique

2024

Novel TB vaccines

Anticipating tuberculosis vaccine acceptability in Kenya and South Africa

2015-2026

Novel TB vaccines

Assesses willingness to receive a new TB vaccine and explores attitudes, vaccine confidence, hesitancy, information needs and factors influencing potential uptake among adults, adolescents and caregivers in southern Mozambique. The study used surveys and in-depth interviews and found 77% willingness to receive a new TB vaccine among adults and adolescents.

Tuberculosis research principles and priorities in children and adolescents

2024-2026

Novel TB vaccines

An international consensus process led by the WHO Child and Adolescent TB Working Group to identify priority research areas for TB prevention, diagnosis, treatment and care in children and adolescents. Importantly for your database, one of the agreed research priorities is the development of effective TB vaccines, alongside research into feasibility, acceptability and uptake of interventions.