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How can new TB vaccines be effectively introduced in Indonesia?

2026

Explores how Indonesia could prepare for and successfully introduce a new adult TB vaccine. It brought together 28 stakeholders form TB, immunisation and international organisations to examine potential target popualtions, delievery strategies, financing , vaccine accpetability, helath system readinessfor vaccine introduction

BCG arthirtis in a patient with SCID

2025-2026

BCG vaccine

Highlights the risk of serious BCG complications in infants eith undiagnosed SCID. It emphasizes the need for immunodeficiency screening before BCG vacciantion to ensure safe vaccine delivery. The study is relevant to accessible TB vaccination through appropriate implementation and screeening strategies

Disseminated BCGosis in immunocompromised infants

2026

BCG vaccine

Case series that describes disseminated BCG disease in five immunocompromised infants following BCG vaccination. It highlights the safety risks of BCG vaccination in infants with undiagnosed immunodeficiency and the importance of identifying the high-risk infants before vaccination. The findings are particularly relevant to national BCG vaccination policy and the safe implementation of TB vaccination programmes

Knowledge of maternity caregivers on vaccination BCG recommendations and circuits

2026

BCG vaccine

Study asses maternity caregivers' knowledge of BCG vaccination recommendations and vaccination pathways. It identifies gaps in healthcare workers' knowledge that may affect the appropriate delivery of BCG vaccination

Asymptomatic TB

2026

The study investigates the biological characteristics of asymptomatic TB and identifies two distinct subtypes with different disease severity. It highlights the difficulty of detecting asymptomatic TB using current screening approaches and the potential for undetected individuals to contribute to TB transmission

Non-Specific Effects of Bacillus Calmette-Guérin

2023

BCG vaccine

Systamtic review and meta-alysis evaluates whether BCG vaccination has non-specific effects beyond protection against tuebrculosis. It analyses 16 randomized controlled trials involving 34,197 participants and examines outcomes including mortality, infections and hospitalisation.

Progress and challenges in TB vaccine development

2017-2018

BCG vaccine, Hypothetical vaccines

This review examines the development pipeline for new TB vaccines and the challenges involved in moving vaccine candidates from preclinical research through clinical trials and eventual introduction. It discusses different vaccine platforms and candidates, clinical trial design, immune correlates of protection, regulatory requirements, funding, and the need for coordinated development programmes. It also highlights key barriers that could delay the availability of an effective TB vaccine and discusses the priorities for accelerating vaccine development

Prevention is better than cure’: a mixed methods study of communities’ and healthcare workers’ perspectives on new adult and adolescent TB vaccines and their implementation in Zambia

2024

Hypothetical vaccines

Mixed methods study examining community members' and healthcare workers' views on future TB vaccines for adults and adolescents in Zamibia/ It assesses willingness to receive a TB vaccine, preferred vaccine characteristics, concerns about safety and efficacy, trusted information sources, barriers to uptake, and preferred approaches for vaccine delivery and implementation