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Optimising DTwP-containing vaccine infant immunisation schedules in Uganda and Nepal (OptImms)

2021-2025

Evaluates alternative infant immunisation schedules in Uganda and Nepal to determine whether reduced-dose or delayed schedules can maintain adequate protection while creating space in routine immunisation programmes for the introduction of new vaccines.

Impact of introducing RTS,S/AS01E malaria vaccine on mortality in young children in Ghana, Kenya, and Malawi

2019=2023

RTS,S/AS01E Malaria vaccine

Evaluates the real-world introduction of the RTS,S/AS01E malaria vaccine through a large sclae cluster randomised implementation programme. The study provides evidence on the impact of vaccine introduction through routine immunisation systems and is relevant to understanding practical vaccine implementation and preparedness

Attitudes towards new tuberculosis vaccines among adults, adolescents and their caregivers in southern Mozambique

2024

Novel TB vaccines

Anticipating tuberculosis vaccine acceptability in Kenya and South Africa

2015-2026

Novel TB vaccines

Assesses willingness to receive a new TB vaccine and explores attitudes, vaccine confidence, hesitancy, information needs and factors influencing potential uptake among adults, adolescents and caregivers in southern Mozambique. The study used surveys and in-depth interviews and found 77% willingness to receive a new TB vaccine among adults and adolescents.

Vaccination policies for healthcare personnel in Europe, 2026

2026

BCG vaccine

Comparative study of vaccination policies for healthcare personnel acorss 32 European countries, examining which vaccines are recommended or mandatory, which healhtcare personnel are targeted and how policies have changed since 2018. It includes policies for BCG/TB vaccination, as well as influenza, Covid-19, hepatitis B, MMR, varicella, pertusis, and other vaccines

BCG arthirtis in a patient with SCID

2025-2026

BCG vaccine

Highlights the risk of serious BCG complications in infants eith undiagnosed SCID. It emphasizes the need for immunodeficiency screening before BCG vacciantion to ensure safe vaccine delivery. The study is relevant to accessible TB vaccination through appropriate implementation and screeening strategies

Disseminated BCGosis in immunocompromised infants

2026

BCG vaccine

Case series that describes disseminated BCG disease in five immunocompromised infants following BCG vaccination. It highlights the safety risks of BCG vaccination in infants with undiagnosed immunodeficiency and the importance of identifying the high-risk infants before vaccination. The findings are particularly relevant to national BCG vaccination policy and the safe implementation of TB vaccination programmes

Knowledge of maternity caregivers on vaccination BCG recommendations and circuits

2026

BCG vaccine

Study asses maternity caregivers' knowledge of BCG vaccination recommendations and vaccination pathways. It identifies gaps in healthcare workers' knowledge that may affect the appropriate delivery of BCG vaccination

Asymptomatic TB

2026

The study investigates the biological characteristics of asymptomatic TB and identifies two distinct subtypes with different disease severity. It highlights the difficulty of detecting asymptomatic TB using current screening approaches and the potential for undetected individuals to contribute to TB transmission

Non-Specific Effects of Bacillus Calmette-Guérin

2023

BCG vaccine

Systamtic review and meta-alysis evaluates whether BCG vaccination has non-specific effects beyond protection against tuebrculosis. It analyses 16 randomized controlled trials involving 34,197 participants and examines outcomes including mortality, infections and hospitalisation.